• Catherine L Lawson, Rutgers University
• Helen M Berman, Rutgers University
• Brinda Vallat, Rutgers University
• Li Chen, Rutgers University
• Craig L Zirbel, Bowling Green State University
• Neocles B Leontis, Bowling Green State University (deceased)

• Helen M Berman, Rutgers University
• Wilma K Olson, Rutgers University
• David Beveridge, Wesleyan University

The Nucleic Acid Knowledge Base (NAKB), modern successor to the Nucleic Acid Database (NDB) Project, archives and distributes structural information about nucleic acids. Development and implementation of NAKB has been funded by the National Institutes of Health R01 GM085328. NDB has been funded by National Science Foundation and the Department of Energy in the past.

NAKB's home is the Institute for Quantitative Biomedicine, Rutgers University, 174 Frelinghuysen Rd, Piscataway, NJ USA, 08854-8076

Researchers who use NAKB should cite:

• Lawson CL, Berman HM, Vallat B, Chen L, Zirbel C (2024) The Nucleic Acid Knowledgebase: a new portal for 3D structural information about nucleic acids. Nucleic Acids Research 52, D245-D254. DOI

Researchers who use the NDB should cite:

• Berman HM, Olson WK, Beveridge DL, Westbrook J, Gelbin A, Demeny T, Hsieh SH, Srinivasan AR, Schneider B (1992) The Nucleic Acid Database: A Comprehensive Relational Database of Three-Dimensional Structures of Nucleic Acids. Biophys. J. 63, 751-759. DOI
• Coimbatore Narayanan B, Westbrook J, Ghosh S, Petrov AI, Sweeney B, Zirbel CL, Leontis NB, Berman HM (2014) The Nucleic Acid Database: new features and capabilities. Nucleic Acids Res 42, D114-22. DOI

The history of NDB and plan for NAKB are described here:

• Berman HM, Lawson CL, Schneider B (2022) Developing Community Resources for Nucleic Acid Structures. Life 12, 540. DOI

Please send questions, comments, suggestions about NAKB to help@nakb.org.

NAKB is currently updated weekly on Thursdays, ~noon US ET (timing may change in future). Current update info is shown in the banner at the top of every page.

NAKB Feature(s)		Software
2D fold diagrams		RNAview v.2.0
NA parameter tables, annotations		X3DNA-DSSR v.2.4
NA and Protein Sequence Clusters		CD-HIT, CD-HIT-ESTv.4.8.1
template-based 2D fold viewer		R2DTv.1.3
3D visualization		Mol*