2025-01-08 : 18794 3D structures containing nucleic acids | RNAEQ v3.369all
NAKB entry image
Released2016-05-18Deposited: 2016-03-24
TitleHuman holo-PIC in the initial transcribing state (no IIS)
AuthorsHe Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I, Nogales E
MethodELECTRON MICROSCOPY6.3 Å
SINGLE PARTICLESoftware: RELION
Primary CitationNear-atomic resolution visualization of human transcription promoter opening. He Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I, Nogales E Nature (2016)
Entry ContentDeposited MW: 1182.77 kDa
Analysis
Protein Annotations
TypeDescription (hover for sequence)Chains(Auth)SourceMW(kDa)Links
DNASCP-X (83-MER)XHomo sapiens25.8
SCP-Y (83-MER)YHomo sapiens25.4
RNARNA (6-MER)ZHomo sapiens1.9
ProteinDNA-directed RNA polymerase II subunit RPB1AHomo sapiens217.4
DNA-directed RNA polymerase II subunit RPB2BHomo sapiens134.1
DNA-directed RNA polymerase II subunit RPB3CHomo sapiens31.5
DNA-directed RNA polymerase II subunit RPB4DHomo sapiens16.3
DNA-directed RNA polymerase II subunit RPB5EHomo sapiens24.6
DNA-directed RNA polymerase II subunit RPB6FHomo sapiens14.5
DNA-directed RNA polymerase II subunit RPB7GHomo sapiens19.3
DNA-directed RNA polymerase II subunit RPB8HHomo sapiens17.2
DNA-directed RNA polymerase II subunit RPB9IHomo sapiens14.5
DNA-directed RNA polymerase II subunit RPB10JHomo sapiens7.7
DNA-directed RNA polymerase II subunit RPB11-aKHomo sapiens13.3
DNA-directed RNA polymerase II subunit RPB12LHomo sapiens7
Transcription initiation factor IIBMHomo sapiens34.9
Transcription initiation factor IIA subunit 1NHomo sapiens41.5
Transcription initiation factor IIA subunit 2OHomo sapiens12.5
TATA-box-binding proteinPHomo sapiens37.7
General transcription factor IIE subunit 1QHomo sapiens49.5
Transcription initiation factor IIE subunit betaRHomo sapiens33.1
General transcription factor IIF subunit 1SHomo sapiens58.3
General transcription factor IIF subunit 2THomo sapiens28.4
TFIIH basal transcription factor complex helicase XPB subunitVHomo sapiens89.4
TFIIH basal transcription factor complex helicase XPD subunitWHomo sapiens87
General transcription factor IIH subunit 20Homo sapiens44.5
General transcription factor IIH subunit 51Homo sapiens8.1
General transcription factor IIH subunit 42Homo sapiens52.2
General transcription factor IIH subunit 33Homo sapiens34.4
LigandZINC ION0.065
MAGNESIUM ION0.024
Assembly #Type, Components (Author Chain Ids)Oligomer | Point SymmetryActions
1author defined
DNA: SCP-X (83-MER) (X)
DNA: SCP-Y (83-MER) (Y)
Protein: DNA-directed RNA polymerase II subunit RPB1 (A)
Protein: DNA-directed RNA polymerase II subunit RPB10 (J)
Protein: DNA-directed RNA polymerase II subunit RPB11-a (K)
Protein: DNA-directed RNA polymerase II subunit RPB12 (L)
Protein: DNA-directed RNA polymerase II subunit RPB2 (B)
Protein: DNA-directed RNA polymerase II subunit RPB3 (C)
Protein: DNA-directed RNA polymerase II subunit RPB4 (D)
Protein: DNA-directed RNA polymerase II subunit RPB5 (E)
Protein: DNA-directed RNA polymerase II subunit RPB6 (F)
Protein: DNA-directed RNA polymerase II subunit RPB7 (G)
Protein: DNA-directed RNA polymerase II subunit RPB8 (H)
Protein: DNA-directed RNA polymerase II subunit RPB9 (I)
Protein: General transcription factor IIE subunit 1 (Q)
Protein: General transcription factor IIF subunit 1 (S)
Protein: General transcription factor IIF subunit 2 (T)
Protein: General transcription factor IIH subunit 2 (0)
Protein: General transcription factor IIH subunit 3 (3)
Protein: General transcription factor IIH subunit 4 (2)
Protein: General transcription factor IIH subunit 5 (1)
Protein: TATA-box-binding protein (P)
Protein: TFIIH basal transcription factor complex helicase XPB subunit (V)
Protein: TFIIH basal transcription factor complex helicase XPD subunit (W)
Protein: Transcription initiation factor IIA subunit 1 (N)
Protein: Transcription initiation factor IIA subunit 2 (O)
Protein: Transcription initiation factor IIB (M)
Protein: Transcription initiation factor IIE subunit beta (R)
RNA: RNA (6-MER) (Z)
29-meric(29) | C1View Assembly in 3D (Mol*)
View Nucleic Acid Parameters (DSSR)
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